The exact cause of hangovers are not completely understood, but they are a well known problem with ingesting alcohol. Bad alcohol hangovers are considered to be worse than the day-after effects of nearly any other psychoactive. Alcohol causes liver damage and bad hangovers may indicate alcohol toxicity and should be avoided. The primary causes of hangover are believed to be dehydration and related electrolyte imbalance, blood-sugar regulation disturbance, acute withdrawal, toxicity from alcohol metabolites, interaction with congeners (non-alcohol components of drinks), reduced sleep quality, and personal biological profile.
For more information above hangovers, see
Alcohol Hangovers